Rational Design of Selective Submicromolar Inhibitors of Tritrichomonas foetus Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase. Aronov, A.M., Munagala, N.R., Ortiz de Montellano, P.R., Kuntz, I.D., and Wang, C.C. (2000) Biochemistry . 39, 4684-4691. HTML, PDF
Alkylation of a Catalytic Aspartate Group of the SIV Protease by an Epoxide Inhibitor. Caldera, P., Yu, Z., Knegtel, R. M. A., McPhee, F., Burlingame, A., Craik, C. S., Kuntz, I. D., and Ortiz de Montellano, P. R. (1997) Bioorg. Med. Chem. 5, 2019-2027. A bstract, PDF
The Discovery, Characterization, and Crystallographically Determined Binding Mode of an FMOC Containing Inhibitor of the HIV-1 Protease. Rutenber, E. E., De Voss, J. J., Hoffman, L., Stroud, R. M., Lee, K. H., Alvarez, J. C., McPhee, F., Craik, C. S., and Ortiz de Montellano, P. R. (1997) Bioorg. Med. Chem. 5, 1311-1320. A bstract, PDF
Irreversible Inhibition of the HIV-1 Protease: Targeting Alkylating Agents to the Catalytic Aspartate Groups. Wah, Y. Y., Caldera, P., De Voss, J. J., McPhee, F., Burlingame, A., Craik, C. S., Kuntz, I. D., and Ortiz de Montellano, P. R. (1996) J. Am. Chem. Soc. 118, 5846-5856. HTML PDF
Non-Peptide HIV Protease Inhibitors. Differential Introduction of Alkylamino Groups into the Two Aryl Rings of Haloperidol. Lee, K. H., McPhee, F., Craik, C. S., and Ortiz de Montellano, P. R. (1994) J. Org. Chem. 59, 6194-6199.
In Vitro Characterization of Non-Peptide Irreversible Inhibitors of HIV Proteases. Salto, R., Babé, L. M., Li, J., Rosé, J. R., Yu, Z., Burlingame, A., De Voss, J., Sui, Z., Ortiz de Montellano, P. R., and Craik, C. S. (1994) J. Biol. Chem. 269, 10691-10698. Abstract
Haloperidol-Based Irreversible Inhibitors of the HIV-1 and HIV-2 Proteases. De Voss, J., Sui, Z., DeCamp, D. L., Salto, R., Babé, L. M., Craik, C. S., and Ortiz de Montellano, P. R. (1994) J. Med. Chem. 37, 665-673.
Inhibition of Renal Vascular 20-HETE Production Impairs Autoregulation of Renal Blood Flow. Zou, A.-P., Imig, J. D., Kaldunski, M., Ortiz de Montellano, P. R., Sui, Z., and Roman, R. J. (1994) Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35), F275-F282.
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